gestate: Generalised Survival Trial Assessment Tool Environment

Provides tools to assist planning and monitoring of time-to-event trials under complicated censoring assumptions and/or non-proportional hazards. There are three main components: The first is analytic calculation of predicted time-to-event trial properties, providing estimates of expected hazard ratio, event numbers and power under different analysis methods. The second is simulation, allowing stochastic estimation of these same properties. Thirdly, it provides parametric event prediction using blinded trial data, including creation of prediction intervals. Methods are based upon numerical integration and a flexible object-orientated structure for defining event, censoring and recruitment distributions (Curves).

Version: 1.5.0
Depends: R (≥ 4.0.0)
Imports: foreach, doParallel, shiny, shinythemes, survival, methods
Suggests: testthat, knitr, rmarkdown
Published: 2021-11-24
Author: James Bell [aut, cre], Jasmin Ruehl [ctb]
Maintainer: James Bell <james.bell.ext at boehringer-ingelheim.com>
License: GPL-3
NeedsCompilation: no
CRAN checks: gestate results

Documentation:

Reference manual: gestate.pdf
Vignettes: Event Prediction with gestate
Planning Time-To-Event Trials with gestate

Downloads:

Package source: gestate_1.5.0.tar.gz
Windows binaries: r-devel: gestate_1.5.0.zip, r-release: gestate_1.4.0.zip, r-oldrel: gestate_1.5.0.zip
macOS binaries: r-release (arm64): gestate_1.5.0.tgz, r-release (x86_64): gestate_1.5.0.tgz, r-oldrel: gestate_1.5.0.tgz
Old sources: gestate archive

Reverse dependencies:

Reverse suggests: eventTrack

Linking:

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